Diagam

Diagam

Diagam is a Belgian manufacturer specializing in in-vitro diagnostic (IVD) reagents for the measurement of specific proteins. With over 30 years of experience, the company develops and produces high-quality assays based on immunoturbidimetry (classical method), PETIA (Particle-Enhanced Turbidimetric ImmunoAssay), and PECIA (Particle-Enhanced Colorimetric ImmunoAssay) technologies. Diagam’s reagents are designed for clinical chemistry analyzers and are known for excellent precision, stability, and standardization against IFCC and WHO references. Operating from Ghislenghien, Belgium—with sales offices in France, Spain, and Brazil—Diagam supplies both OEM and branded kits worldwide, offering customized solutions and strong regulatory compliance under ISO 9001, ISO 13485, and CE/IVDR certification.

  • Classical Immunoturbidimetric Assays (PETIA):
    Quantitative measurement of serum, plasma, urine, and CSF proteins such as:

    • Albumin (serum, CSF, urine)

    • Alpha-1-antitrypsin, Alpha-1-glycoprotein (orosomucoid), Alpha-2-macroglobulin

    • Apolipoproteins A1 and B

    • Complement C3 and C4, Haptoglobin, Ceruloplasmin, Transferrin

    • Immunoglobulins A, G, M, E (and CSF forms)

    • Prealbumin, Retinol Binding Protein (RBP), Fibrinogen, Microalbumin, Lipoprotein(a)

    • Antistreptolysin O (ASO), Rheumatoid Factor (RF)

  • Nanoparticle-Based Immunoassays (PECIA):

    • Tests using gold nanoparticles for enhanced sensitivity and stability, such as:

      • Calprotectin (fecal) – CalproGold®,

      • Cystatin C, Ferritin, and Rheumatoid Factor (colloidal gold).

  • Calibrators & Controls:

    • Ready-to-use, long-shelf-life materials standardized to IFCC, WHO, NIBSC, ERM-DA470 (CRM 470) standards for analytical accuracy and traceability.

  • Applications:

    • Available for major clinical analyzers, compatible across platforms, with validated protocols and barcoded vials for traceability.

In essence, Diagam’s product line covers the full range of specific protein assays for clinical chemistry and immunology labs, from traditional immunoturbidimetric kits to advanced nanoparticle-enhanced diagnostics.